Janus kinase inhibitors and fields of usage
Ayşenur Saygılı1, Oytun Erbaş2
1Inönü University Molecular Biology and Genetics Graduate, Malatya, Turkey
2Department of Physiology, Demiroğlu Bilim University Faculty of Medicine, Istanbul, Turkey
Keywords: Inhibitor, janus kinase, chromosome, signal path
Abstract
Jak regions have been identified on chromosome 1, 9, and 19. Cytokines and receptors in the janus kinase/signal transducers and activators of transcription pathway are involved in cell signaling. In order to treat damages in the Jak pathway, molecules called inhibitors have been studied and used for treatment.