Uterus transplantation

Abstract

Successful births have been performed thanks to uterus transplantations to recipients from living donors. Females who are infertile due to nonfunctional uterus can be treated. The live donor operation included in uterus transplantation lasts for more than 10 hours and the recipient is administered immunosuppressive drug treatment for years after the transplantation of the uterus to prevent the rejection of the uterus. Immunosuppressive drugs are associated with significant side effects including high-level kidney toxicity, severe infection risk, and diabetes. For this reason, alternative approaches should be developed to treat uterine factor infertility.